Structure of PDB 8spu Chain C Binding Site BS02

Receptor Information
>8spu Chain C (length=107) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNI
QAVLLPK
Ligand information
>8spu Chain I (length=149) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgcctccccatgtgggacctggagaaacagagggtggagggagcatag
agagtctgttctaagctgcaaagcaaaggcctggcgacctaggagaccat
ggagttccagaaagtgatagttatgcagagcgaatggagggaatcagca
Receptor-Ligand Complex Structure
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PDB8spu Structural mechanism of LIN28B nucleosome targeting by OCT4.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		K15 S16 R17 R20 R32 R77
Binding residue
(residue number reindexed from 1)		K4 S5 R6 R9 R21 R66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8spu, PDBe:8spu, PDBj:8spu
PDBsum8spu
PubMed37327775
UniProtQ16777|H2A2C_HUMAN Histone H2A type 2-C (Gene Name=H2AC20)

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