Structure of PDB 8r3k Chain C Binding Site BS02
Receptor Information
>8r3k Chain C (length=249) Species:
1318616
(Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9))) [
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MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWM
MAMKYPITADKRIMEMIPERNEQRQTLWSKTNDAGSDRVMVSPLAVTWWN
RNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPG
HADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKKELQDCKIAP
LMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGE
Ligand information
>8r3k Chain M (length=10) [
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ggggaaaaua
..........
Receptor-Ligand Complex Structure
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PDB
8r3k
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome.
Resolution
3.43 Å
Binding residue
(original residue number in PDB)
K33 P43 Y205
Binding residue
(residue number reindexed from 1)
K33 P43 Y205
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003968
RNA-dependent RNA polymerase activity
Biological Process
GO:0001172
RNA-templated transcription
GO:0006351
DNA-templated transcription
GO:0006370
7-methylguanosine mRNA capping
GO:0019083
viral transcription
GO:0039523
symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694
viral RNA genome replication
GO:0075526
cap snatching
Cellular Component
GO:0033650
host cell mitochondrion
GO:0042025
host cell nucleus
GO:0044423
virion component
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8r3k
,
PDBe:8r3k
,
PDBj:8r3k
PDBsum
8r3k
PubMed
38316757
UniProt
X5F427
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