Structure of PDB 8qfd Chain C Binding Site BS02

Receptor Information
>8qfd Chain C (length=355) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPY
AVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMF
APTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPL
VVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRI
QRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIW
TESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRAL
RAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVD
KAAAA
Ligand information
>8qfd Chain 8 (length=144) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagcu
agcugcgagaauuaaugugaauugcaggcgaucaucgacacuucgaacgc
acuugcggccccgggcccggggcuacgccugucugagcgucgcu
........................................<<<<<<<<<.
...>>>>.....<.<<<......>>.......>>>..>...>>>....<<
....>><<<<<<<<<>>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB8qfd The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons
Resolution2.2 Å
Binding residue
(original residue number in PDB)		P51 A53 S55 K195 M196
Binding residue
(residue number reindexed from 1)		P49 A51 S53 K193 M194
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qfd, PDBe:8qfd, PDBj:8qfd
PDBsum8qfd
PubMed38383789
UniProtP36578|RL4_HUMAN Large ribosomal subunit protein uL4 (Gene Name=RPL4)

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