Structure of PDB 8ovj Chain C Binding Site BS02

Receptor Information
>8ovj Chain C (length=366) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPSVSVYSASSDSVVGTCPLPAVFTAPIRSDIVKFVHTNMAKNSRQAYAV
NRLSGMNHSAHSWGTGRAVARIPRISGGGTSTSGAGAFGNMCRGGRMFAP
TKIFRRWHRKINLHQKRFAVVSALAASSVPSLVMSRGHQIGNVPEVPLVV
EDSIQGYEKTKEAMAFLKAIAAIDDVNRVNDSREIRAGRGKMRNRRYVAR
RGPMLVMPNNKGTRAFRNIFGLDLANVSALNLLHLAPGGHVGRFVIWTQS
AFEQLDKIFGTFTEASAVKKGFTLPAPMLTNTDVTRIMQSEEVRRVLKPK
KLQAKKASRFQTPTNGMKNRRLRLRLNPYVKRETAAAKGMRNVANRDARR
KAKLARVTKAKKAATK
Ligand information
>8ovj Chain 7 (length=164) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacgugucgcgauggaugacuuggcuuccuauuucguugaagaacgcagu
aaagugcgauaagugguaucaauugcagaacauucaauuaccgaaucuuu
gaacgcaaacggcgcaugggagaagcucgugucauccccgugcaugccau
auucucagugucga
.........................................<<<<<<.((
.....>>>.....<<<<<......))............>>>>.>...>>>
....<<.....>><<<<<<<....<<....>>....>>>>>>>.......
..............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ovj Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		A50 A52 N54 K194
Binding residue
(residue number reindexed from 1)		A47 A49 N51 K191
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ovj, PDBe:8ovj, PDBj:8ovj
PDBsum8ovj
PubMed38722744
UniProtE9ADW5

[Back to BioLiP]