Structure of PDB 8jkn Chain C Binding Site BS02

Receptor Information
>8jkn Chain C (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAAL
FKAWALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISD
PYKVYRIVP
Ligand information
Receptor-Ligand Complex Structure
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PDB8jkn Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		G22 L24 W74 K78 K80 R96 C99 K103
Binding residue
(residue number reindexed from 1)		G2 L4 W54 K58 K60 R76 C79 K83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkn, PDBe:8jkn, PDBj:8jkn
PDBsum8jkn
PubMed37683642
UniProtF2Z3D5

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