Structure of PDB 8ilw Chain C Binding Site BS02
Receptor Information
>8ilw Chain C (length=60) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQN
QRAKMKKLAR
Ligand information
>8ilw Chain B (length=16) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
gtttggattaagtgtt
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
8ilw
Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Resolution
2.712 Å
Binding residue
(original residue number in PDB)
R199 T200 W242 N245
Binding residue
(residue number reindexed from 1)
R4 T5 W47 N50
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:8ilw
,
PDBe:8ilw
,
PDBj:8ilw
PDBsum
8ilw
PubMed
UniProt
Q8TE12
|LMX1A_HUMAN LIM homeobox transcription factor 1-alpha (Gene Name=LMX1A)
[
Back to BioLiP
]