Structure of PDB 8ik5 Chain C Binding Site BS02
Receptor Information
>8ik5 Chain C (length=67) Species:
9606
(Homo sapiens) [
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HMHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV
QVWFQNQRAKMKKLARR
Ligand information
>8ik5 Chain B (length=15) [
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ggaagattaaatatg
Receptor-Ligand Complex Structure
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PDB
8ik5
Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Resolution
1.989 Å
Binding residue
(original residue number in PDB)
R199 T200 V241 N245 K249
Binding residue
(residue number reindexed from 1)
R10 T11 V52 N56 K60
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:8ik5
,
PDBe:8ik5
,
PDBj:8ik5
PDBsum
8ik5
PubMed
UniProt
Q8TE12
|LMX1A_HUMAN LIM homeobox transcription factor 1-alpha (Gene Name=LMX1A)
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