Structure of PDB 8ik5 Chain C Binding Site BS02

Receptor Information
>8ik5 Chain C (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV
QVWFQNQRAKMKKLARR
Ligand information
Receptor-Ligand Complex Structure
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PDB8ik5 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Resolution1.989 Å
Binding residue
(original residue number in PDB)
R199 T200 V241 N245 K249
Binding residue
(residue number reindexed from 1)
R10 T11 V52 N56 K60
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:8ik5, PDBe:8ik5, PDBj:8ik5
PDBsum8ik5
PubMed
UniProtQ8TE12|LMX1A_HUMAN LIM homeobox transcription factor 1-alpha (Gene Name=LMX1A)

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