Structure of PDB 8hxy Chain C Binding Site BS02

Receptor Information
>8hxy Chain C (length=109) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPN
IQSVLLPKK
Ligand information
>8hxy Chain J (length=170) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aatacatgcacaggatgtatatatctgacacgtgcctggagactagggag
taatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaa
gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
ctccagtctagaactggcag
Receptor-Ligand Complex Structure
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PDB8hxy Structure of histone deacetylase complex Rpd3S bound to nucleosome
Resolution3.1 Å
Binding residue
(original residue number in PDB)
R11 A12 K15 T16 R17 R29 R32 R77
Binding residue
(residue number reindexed from 1)
R1 A2 K5 T6 R7 R19 R22 R67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8hxy, PDBe:8hxy, PDBj:8hxy
PDBsum8hxy
PubMed37798513
UniProtP06897|H2A1_XENLA Histone H2A type 1

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