Structure of PDB 8giy Chain C Binding Site BS02

Receptor Information
>8giy Chain C (length=367) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKT
SIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKF
LLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRA
LQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSL
VEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAAL
GNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMT
LLRALAFHPRMPLPEPE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8giy Chain C Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8giy Structural characterisation of the complete cycle of sliding clamp loading in E. coli
Resolution3.7 Å
Binding residue
(original residue number in PDB)		C76 C79
Binding residue
(residue number reindexed from 1)		C74 C77
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8giy, PDBe:8giy, PDBj:8giy
PDBsum8giy
PubMed
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

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