Structure of PDB 8ev3 Chain C Binding Site BS02

Receptor Information
>8ev3 Chain C (length=362) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAARPTVSIYNKDGSVSSETLALPFVFKAPIRPDLVRSVHTAVAKNKRQP
YAVSEKAGHQTSAESWGTGRALARIPRVGGGGTHRSGQAAFGNMCRSGRM
FAPTKTWRKWHVKVNQNEKRYAIASAVAASGVPSLLLARGHRIEEIPEVP
LVVDDAVQSFQKTKEAVALLKEIKAYRDVIKVANSRKLRAGKGKLRNRRH
VQRRGPLVVFNEDTGIVKAFRNIPGVEIVNVRRLNLLQLAPGGHLGRFVI
WTKSAFGLLDSVFGSTTEVAQLKKNYFLPENIISNADVTRLINSDEIQSI
VKAAGPSRVKRAHVQKKNPLKNKAVLSRLNPYAKAYKANVKINSEKTPKA
AGEKFLSVLHEN
Ligand information
>8ev3 Chain 2 (length=150) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaaacuuucagcaacggaucucuuggcucucgcaucgaugaagaacgcag
cgaaaugcgauacguaaugugaauugcagaagaaucaucgaaucuuugaa
cgcacugcgccuuuggguucuaccaaaggcaugccuguuugagugucauu
..........................................<<<<<<<<
.....>>>>.....<.<<<.......>........>>>..>...>>>...
.<<...>><<<<<<<<......>>>>>>>>....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ev3 Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		P51 A53 S55 T107 K195
Binding residue
(residue number reindexed from 1)		P50 A52 S54 T106 K194
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ev3, PDBe:8ev3, PDBj:8ev3
PDBsum8ev3
PubMed36423630
UniProtQ9P784|RL4B_SCHPO Large ribosomal subunit protein uL4B (Gene Name=rpl401)

[Back to BioLiP]