Structure of PDB 8cu0 Chain C Binding Site BS02

Receptor Information
>8cu0 Chain C (length=130) Species: 86665 (Halalkalibacterium halodurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFL
AIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWKL
VDEAEEWLNTHTYETPILKWQTDKWGEIKA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cu0 Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		N77 T104 N106 K138 W139 S147 T148
Binding residue
(residue number reindexed from 1)		N16 T43 N45 K77 W78 S86 T87
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:8cu0, PDBe:8cu0, PDBj:8cu0
PDBsum8cu0
PubMed35973057
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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