Structure of PDB 8co4 Chain C Binding Site BS02
Receptor Information
>8co4 Chain C (length=379) Species:
3702
(Arabidopsis thaliana) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
MATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTD
AYTWSGKDPEGLFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECR
ECKFCKSGKTNLCGKVRSATGVGIMMNDRKSRFSVNGKPIYHFMGTSTFS
QYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNTAKVEPGSNVAI
FGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPKDHD
KPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAAS
GQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYIT
HNLTLGEINKAFDLLHEGTCLRCVLDTSK
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
8co4 Chain C Residue 402 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
8co4
Structural and biochemical characterization of Arabidopsis alcohol dehydrogenases reveals distinct functional properties but similar redox sensitivity.
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
C47 H69 C177
Binding residue
(residue number reindexed from 1)
C47 H69 C177
Annotation score
1
Enzymatic activity
Enzyme Commision number
1.1.1.-
1.1.1.1
: alcohol dehydrogenase.
1.1.1.284
: S-(hydroxymethyl)glutathione dehydrogenase.
Gene Ontology
Molecular Function
GO:0004022
alcohol dehydrogenase (NAD+) activity
GO:0008270
zinc ion binding
GO:0016491
oxidoreductase activity
GO:0046872
metal ion binding
GO:0051903
S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity
GO:0080007
S-nitrosoglutathione reductase (NADH) activity
GO:0106321
S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity
GO:0106322
S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity
Biological Process
GO:0044281
small molecule metabolic process
GO:0046294
formaldehyde catabolic process
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:8co4
,
PDBe:8co4
,
PDBj:8co4
PDBsum
8co4
PubMed
38308388
UniProt
Q96533
|ADHX_ARATH Alcohol dehydrogenase class-3 (Gene Name=ADH2)
[
Back to BioLiP
]