Structure of PDB 8cec Chain C Binding Site BS02

Receptor Information
>8cec Chain C (length=708) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEAFMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEK
GLIVRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDTSLSDVFIPPNE
LNTAMNGDIVMVRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGF
VIPDDKKITSDIFIPKNGKNGAAEGHKVVVKLTSYPEGRMNAEGEVETIL
GHKNDPGIDILSVIHKHGLPGEFPADAMEQASSTPDTIDEKDLKDRRDLR
DQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHYVTENSPIDK
EALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQ
VTEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLVPMFKDMERL
AQILRDKRMDRGAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFM
LVANETVAEHFHWMNVPFIYRIHEEPNAEKLQKFLEFVTTFGYVVKGTAG
NIHPRALQSILDAVRDRPEETVISTVMLRSMKQAKYDPQSLGHFGLSTEF
YTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERLPDIAEHTSS
MERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPNTIE
GLVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERN
IDFEIVGM
Ligand information
Receptor-Ligand Complex Structure
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PDB8cec Structural basis of ribosomal 30S subunit degradation by RNase R
Resolution3.57 Å
Binding residue
(original residue number in PDB)		D260 D269 Y312 F418 F420 E422 R439 H475 L530 R531 Q535 A536 H545 Y553 R561 R562 R612 E652
Binding residue
(residue number reindexed from 1)		D258 D267 Y310 F416 F418 E420 R437 H473 L528 R529 Q533 A534 H543 Y551 R559 R560 R610 E650
Enzymatic activity
Enzyme Commision number 3.1.13.1: exoribonuclease II.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
Biological Process
GO:0006402 mRNA catabolic process
GO:0016070 RNA metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8cec, PDBe:8cec, PDBj:8cec
PDBsum8cec
PubMed38326618
UniProtO32231|RNR_BACSU Ribonuclease R (Gene Name=rnr)

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