Structure of PDB 8btg Chain C Binding Site BS02

Receptor Information
>8btg Chain C (length=334) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKT
HLMHAIGHYVIDHNPSAKVVYLSSEKFTNEFINSIRDNKAVDFRNRYRNV
DVLLIDDIQFLAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLE
DRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQI
DSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPKVITIKEIQRV
VGQQFNIKLEDFKAKKRTKSVAFPRQIAMYLSREMTDSSLPKIGEEFGGR
DHTTVIHAHEKISKLLADDEQLQQHVKEIKEQLK
Ligand information
>8btg Chain Y (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tagtagaagtaatagtagggcctgtggatttgtggataagt
Receptor-Ligand Complex Structure
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PDB8btg The bacterial replication origin BUS promotes nucleobase capture.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
E183 I190 I193 N196 R202 F218 K222 Q224 T225 L427 D430 D431 Q433 L434 H437
Binding residue
(residue number reindexed from 1)
E75 I82 I85 N88 R94 F110 K114 Q116 T117 L315 D318 D319 Q321 L322 H325
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006275 regulation of DNA replication
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:1990101 DnaA-oriC complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8btg, PDBe:8btg, PDBj:8btg
PDBsum8btg
PubMed38097584
UniProtP05648|DNAA_BACSU Chromosomal replication initiator protein DnaA (Gene Name=dnaA)

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