Structure of PDB 8bav Chain C Binding Site BS02

Receptor Information
>8bav Chain C (length=264) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANL
HKVKQQFMTTSKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQ
IWRKYDADSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFD
RNKDGRLDLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVS
KTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQ
KSELALCLGLKINP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8bav Chain C Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bav Calmodulin type regulator (Homo sapiens) with peptide ligand
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D162 N164 D166 R168
Binding residue
(residue number reindexed from 1)		D150 N152 D154 R156
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration
GO:1900271 regulation of long-term synaptic potentiation
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0030425 dendrite
GO:0030658 transport vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0043195 terminal bouton
GO:0045202 synapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bav, PDBe:8bav, PDBj:8bav
PDBsum8bav
PubMed38593081
UniProtO76038|SEGN_HUMAN Secretagogin (Gene Name=SCGN)

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