Structure of PDB 7xvn Chain C Binding Site BS02

Receptor Information
>7xvn Chain C (length=81) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCAYSCTRQQNCPIDRT
SRNRCQHCRLQKCLALGMSRDAVKFGRMSKK
Ligand information
Receptor-Ligand Complex Structure
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PDB7xvn Structural basis for DNA recognition feature of retinoid-related orphan receptors
Resolution2.302 Å
Binding residue
(original residue number in PDB)
G40 I41 Y43 K52 R56 V101 K102 F103 R105
Binding residue
(residue number reindexed from 1)
G14 I15 Y17 K26 R30 V73 K74 F75 R77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7xvn, PDBe:7xvn, PDBj:7xvn
PDBsum7xvn
PubMed38309263
UniProtP51450|RORG_MOUSE Nuclear receptor ROR-gamma (Gene Name=Rorc)

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