Structure of PDB 7x1n Chain C Binding Site BS02

Receptor Information
>7x1n Chain C (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGF
Ligand information
Receptor-Ligand Complex Structure
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PDB7x1n Functional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion.
Resolution3.315 Å
Binding residue
(original residue number in PDB)		G2 R3 T20 R24 K30
Binding residue
(residue number reindexed from 1)		G1 R2 T19 R23 K29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:7x1n, PDBe:7x1n, PDBj:7x1n
PDBsum7x1n
PubMed35544603
UniProtQ14814|MEF2D_HUMAN Myocyte-specific enhancer factor 2D (Gene Name=MEF2D)

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