Structure of PDB 7uv6 Chain C Binding Site BS02

Receptor Information
>7uv6 Chain C (length=213) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQIRKSHDGICEIHVAKYAE
IFGLTSAEASKDIRQALKSFAGKEVVFYYESFPWFIKPAHSPSRGLYSVH
INPYLIPFFINRFTQFRLSETKEITNPYAMRLYESLCQYRKPDGSGIVSL
KIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRTPMRLSYIEKKKGR
QTTHIVFSFRDIT
Ligand information
Receptor-Ligand Complex Structure
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PDB7uv6 Designed crystalline assemblies of protein and DNA enable site-specific installation of a guest protein, DNA, and small molecule.
Resolution2.72 Å
Binding residue
(original residue number in PDB)
S75 S79 K80 R83 R124 G125 Y127 N159 Q196 S197 Y198 D203 R207
Binding residue
(residue number reindexed from 1)
S56 S60 K61 R64 R94 G95 Y97 N126 Q163 S164 Y165 D170 R174
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006276 plasmid maintenance
GO:0071897 DNA biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:7uv6, PDBe:7uv6, PDBj:7uv6
PDBsum7uv6
PubMed37407546
UniProtP03856|REPE1_ECOLI Replication initiation protein (Gene Name=repE)

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