Structure of PDB 7ttn Chain C Binding Site BS02

Receptor Information
>7ttn Chain C (length=521) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGR
GKATISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAE
FLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRK
LLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKMIGIKKVQGG
ALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNA
EIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYF
ADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQI
GGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKND
SVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNA
GFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRINAL
TAASEAACLIVSVDETIKNPR
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain7ttn Chain C Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ttn Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		D61 G62 T94 K166 D391
Binding residue
(residue number reindexed from 1)		D58 G59 T91 K163 D388
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7ttn, PDBe:7ttn, PDBj:7ttn
PDBsum7ttn
PubMed36493755
UniProtQ99832|TCPH_HUMAN T-complex protein 1 subunit eta (Gene Name=CCT7)

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