Structure of PDB 7tf6 Chain C Binding Site BS02

Receptor Information

>7tf6 Chain C (length=438) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMF
DGSSIEGFVRIEESDMYLHPDLDTWVIFPWGKVARLICDVYKTDGTPFEG
DPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGY
FDLAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVT
ACDNIQTFKLVVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKEN
AFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKRLVPGYEAP
CYIAWSGKNRSPLIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLD
GIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENEVIK
KALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY

Ligand information

>7tf6 Chain P (length=11) Species: 1280 (Staphylococcus aureus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PINRGDLSRFI

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7tf6 Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Resolution	2.15 Å
Binding residue (original residue number in PDB)	F62 R64 I65 Y429
Binding residue (residue number reindexed from 1)	F58 R60 I61 Y421

Enzymatic activity

Enzyme Commision number

6.3.1.2: glutamine synthetase.

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0004356	glutamine synthetase activity
GO:0005524	ATP binding
GO:0016874	ligase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006542	glutamine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:7tf6, PDBe:7tf6, PDBj:7tf6
PDBsum	7tf6
PubMed	35778410
UniProt	E3VXC2

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