Structure of PDB 7pmq Chain C Binding Site BS02

Receptor Information
>7pmq Chain C (length=458) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKT
GSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLP
NTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNT
LVMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQ
RDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCN
TKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATD
VAARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEE
AQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGD
VLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGK
TCRVRLLK
Ligand information
>7pmq Chain F (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaaggguuucgacccuucccaauauggcuguucgccauuu
<<<<<<<<......>>>>>>>><<.<<<<<.....>>>>>>>
Receptor-Ligand Complex Structure
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PDB7pmq Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution3.22 Å
Binding residue
(original residue number in PDB)		K252 W320 E348 R352
Binding residue
(residue number reindexed from 1)		K253 W321 E349 R353
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pmq, PDBe:7pmq, PDBj:7pmq
PDBsum7pmq
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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