Structure of PDB 7mt2 Chain C Binding Site BS02

Receptor Information
>7mt2 Chain C (length=272) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGRGGRNAHGRITT
RHKGGGHKRAYRMIDFRRNDKDGVNAKVAHIEYDPNRTARIALLHYLDGE
KRYIIAPNGLSQGDVVESGANADIKPGNNLPLRNIPAGTLIHAVELRPGG
GAKLARSAGSSIQLLGKEASYASLRMPSGEIRRVDVRCRATVGEVGNAEQ
ANINWGKAGRMRWKGKRPSVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWG
KPEGRTRNANKSSNKFIVRRRR
Ligand information
>7mt2 Chain a (length=1519) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac
augcaagucgaacggaaaggucucuucggagauacucgaguggcgaacgg
gugaguaacacgugggugaucugcccugcacuucgggauaagccugggaa
acugggucuaauaccggauaggaccacgggaugcaugucuugugguggaa
agcgcuuuagcggugugggaugagcccgcggccuaucagcuuguuggugg
ggugacggccuaccaaggcgacgacggguagccggccugagagggugucc
ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu
ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcguggg
ggaugacggccuucggguuguaaaccucuuucaccaucgacgaagguccg
gguucucucggauugacgguagguggagaagaagcaccggccaacuacgu
gccagcagccgcgguaauacguagggugcgagcguuguccggaauuacug
ggcguaaagagcucguaggugguuugucgcguuguucgugaaaucucacg
gcuuaacugugagcgugcgggcgauacgggcagacuagaguacugcaggg
gagacuggaauuccugguguagcgguggaaugcgcagauaucaggaggaa
caccgguggcgaaggcgggucucugggcaguaacugacgcugaggagcga
aagcguggggagcgaacaggauuagauacccugguaguccacgccguaaa
cgguggguacuagguguggguuuccuuccuugggauccgugccguagcua
acgcauuaaguaccccgccuggggaguacggccgcaaggcuaaaacucaa
aggaauugacgggggcccgcacaagcggcggagcauguggauuaauucga
ugcaacgcgaagaaccuuaccuggguuugacaugcacaggacgcgucuag
agauaggcguucccuuguggccugugugcagguggugcauggcugucguc
agcucgugucgugagauguuggguuaagucccgcaacgagcgcaacccuu
gucucauguugccagcacguaaugguggggacucgugagagacugccggg
gucaacucggaggaagguggggaugacgucaagucaucaugccccuuaug
uccagggcuucacacaugcuacaauggccgguacaaagggcugcgaugcc
gcgagguuaagcgaauccuuaaaagccggucucaguucggaucggggucu
gcaacucgaccccgugaagucggagucgcuaguaaucgcagaucagcaac
gcugcggugaauacguucccgggccuuguacacaccgcccgucacgucau
gaaagucgguaacacccgaagccaguggccuaacccucgggagggagcug
ucgaaggugggaucggcgauugggacgaagucguaacaagguagccguac
cggaaggugcggcuggauc
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<.<..<<...<<....>>....>>>..>>>>>......
<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<....
..>>>>>......>>>>.....<<<<<<<<<<....>>>>>>>>>>....
.<<......>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<
<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>
>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>
>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<
<......<<<<<..>>>>>.....>>>>...<.<<<<<......<<<<.<
<.....>>..>>>>.......>>>>>....>..<<<<<(((...<<<<<.
....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........
<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<
<.....>>>>>>>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<
<<<<<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>...
........<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>..
..<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>......
....<<<<<<..<<<<<<<<<<<.........>>>>>>>>>>>...<<..
))>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..
)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<.
.......>>..........<<<<<<<......<<<<<<<..<<<.<.<..
..>.>.>>>............>>>>>>>.<<<.<<<..<<<<<<......
.<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<
.<<<<<<....<...<<<......>>>.>.....>>>>>>.....<<<<<
.....>>>>>........>>>>.........>>>...>>>>>>>>>...>
>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<...<<<
....>>>...>>....>>>.....>>>>>>>......<....<<<<<<<.
.......>>>>>>>....>.....>>>>>>....<<<<<<<.........
.>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<
<<..<<<<<<..<<<<....<.<<<<..<<<..<<<..>>>.>>>.>>>>
.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<
<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7mt2 Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Resolution2.76 Å
Binding residue
(original residue number in PDB)		R176 N203 R270
Binding residue
(residue number reindexed from 1)		R175 N202 R269
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0016740 transferase activity
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mt2, PDBe:7mt2, PDBj:7mt2
PDBsum7mt2
PubMed35064151
UniProtP9WHA5|RL2_MYCTU Large ribosomal subunit protein uL2 (Gene Name=rplB)

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