Structure of PDB 7msz Chain C Binding Site BS02

Receptor Information

>7msz Chain C (length=272) Species: 83332 (Mycobacterium tuberculosis H37Rv)

AIRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGRGGRNAHGRITT
RHKGGGHKRAYRMIDFRRNDKDGVNAKVAHIEYDPNRTARIALLHYLDGE
KRYIIAPNGLSQGDVVESGANADIKPGNNLPLRNIPAGTLIHAVELRPGG
GAKLARSAGSSIQLLGKEASYASLRMPSGEIRRVDVRCRATVGEVGNAEQ
ANINWGKAGRMRWKGKRPSVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWG
KPEGRTRNANKSSNKFIVRRRR

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7msz Chain C Residue 302

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7msz Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): G236 G238
• Binding residue (residue number reindexed from 1): G235 G237
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0016740 transferase activity
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0005886 plasma membrane
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7msz, PDBe:7msz, PDBj:7msz
• PDBsum: 7msz
• PubMed: 35064151
• UniProt: P9WHA5|RL2_MYCTU Large ribosomal subunit protein uL2 (Gene Name=rplB)