Structure of PDB 7mp3 Chain C Binding Site BS02
Receptor Information
>7mp3 Chain C (length=102) Species:
9606
(Homo sapiens) [
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IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRQGFVLSLCHLQK
VKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHC
CT
Ligand information
>7mp3 Chain N (length=10) Species:
32630
(synthetic construct) [
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KFEGYDNEFP
Receptor-Ligand Complex Structure
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PDB
7mp3
Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability.
Resolution
2.55 Å
Binding residue
(original residue number in PDB)
R438 K478 H479 Y480 L481 M495 D496 Q499
Binding residue
(residue number reindexed from 1)
R14 K52 H53 Y54 L55 M69 D70 Q73
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7mp3
,
PDBe:7mp3
,
PDBj:7mp3
PDBsum
7mp3
PubMed
35625882
UniProt
Q14451
|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)
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