Structure of PDB 7mi9 Chain C Binding Site BS02

Receptor Information
>7mi9 Chain C (length=339) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGLPLYVQSPKAYVRKDGDCLVIEEERVRVAEARLGETSQVALFGNATLT
TAALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPET
CLNLARRWIVAKIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMR
APSLEVLLGIEGASAGRYFQHFSRMLRGGDGEGMGFDFTTRNRRPPKDPV
NALLSFAYAMLTREWTVALAAVGLDPYRGFYHQPRFGRPALALDMMEPFR
PLIADSTVLMAINNGEIRTGDFVRSAGGCNLTDSARKRFIAGFERRMEQE
VTHPIFKYTISYRRLLEVQARLLTRYLSGEIPAYPNFVT
Ligand information
>7mi9 Chain H (length=72) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctgtgccgtccgtaacgttgtcgatttttgtattccggggccatgatgcc
ccggcctcattgaagcggcttc
Receptor-Ligand Complex Structure
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PDB7mi9 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Resolution3.89 Å
Binding residue
(original residue number in PDB)		Y232 R234 K235 D236 G237 T269 R544
Binding residue
(residue number reindexed from 1)		Y13 R15 K16 D17 G18 T50 R325
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7mi9, PDBe:7mi9, PDBj:7mi9
PDBsum7mi9
PubMed34588691
UniProtQ74H36|CS4F1_GEOSL CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion (Gene Name=cas4-cas1)

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