Structure of PDB 7lo0 Chain C Binding Site BS02

Receptor Information
>7lo0 Chain C (length=153) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESE
EYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCTY
RGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHI
NWE
Ligand information
Receptor-Ligand Complex Structure
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PDB7lo0 Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Resolution2.71 Å
Binding residue
(original residue number in PDB)		N114 E116 N138 L140 S142 N143
Binding residue
(residue number reindexed from 1)		N113 E115 N137 L139 S141 N142
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006325 chromatin organization
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:7lo0, PDBe:7lo0, PDBj:7lo0
PDBsum7lo0
PubMed35136069
UniProtQ9Y294|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)

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