Structure of PDB 7jk5 Chain C Binding Site BS02

Receptor Information
>7jk5 Chain C (length=590) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADLQHRSYAR
TLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRLHAQRAAM
VCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQLKSWYTNN
FDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVLGVATAMT
AVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTF
KFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSKALGRIKQ
LTHEDMETIRRLPSFRPYVEQIIIAVLTDDDYLKKKLPQLLRDCLLHFLL
FRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTPEYKECLQMLS
FLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLRPKLEAIRLAV
DEVVKGRALQKTLQLIETQIVQDHLRALQDAPPIHELFVFSDIATVRRNI
IGAPRAALHTALNNPHFYMQCKCCETLPDLSVVYKLHLECGRMINLFDWL
QAFRSVVPQIQARFTRAVAELQFLGYIKMSKRKTDHATRL
Ligand information
Receptor-Ligand Complex Structure
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PDB7jk5 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R179 K710 R711
Binding residue
(residue number reindexed from 1)		R134 K581 R582
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7jk5, PDBe:7jk5, PDBj:7jk5
PDBsum7jk5
PubMed32848132
UniProtQ7K2L1

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