Structure of PDB 7e99 Chain C Binding Site BS02

Receptor Information

>7e99 Chain C (length=146) Species: 55676 (Oligobrachia mashikoi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SCCSSEDRANVMHNWDAAWSAAYSDRRVALAQAVFASLFSRDAAAQGLFS
GVSADNPDSADFRAHCVRVVNGLDVAINMLNDPAVLNEQLAHLSAQHQAR
AGVAAAHFDVMAEAFAEVMPQVSSCFSSDSWNRCFARIANGISAGL

Ligand information

InChI=1S/O2/c1-2

MYMOFIZGZYHOMD-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341 OpenEye OEToolkits 1.5.0	O=O

Formula

O2

Name

OXYGEN MOLECULE

PDB chain

7e99 Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	7e99 Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state.
Resolution	2.1 Å
Binding residue (original residue number in PDB)	F50 V70
Binding residue (residue number reindexed from 1)	F49 V69
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005344	oxygen carrier activity
GO:0005506	iron ion binding
GO:0019825	oxygen binding
GO:0020037	heme binding
GO:0046872	metal ion binding

	Biological Process
GO:0001666	response to hypoxia
GO:0015671	oxygen transport

	Cellular Component
GO:0005576	extracellular region
GO:0005833	hemoglobin complex

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Cellular Component

External links

PDB	RCSB:7e99, PDBe:7e99, PDBj:7e99
PDBsum	7e99
PubMed	34804547
UniProt	Q7M418\|GLBB2_OLIMA Extracellular giant hemoglobin major globin subunit B2 (Gene Name=ghbB2)

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