Structure of PDB 7cj9 Chain C Binding Site BS02

Receptor Information
>7cj9 Chain C (length=288) Species: 1727196 (Methylomonas sp. DH-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HSMAFPKRLEIGGHALVWSGDWSAAGARKAIAGAARAGFDYIEIALLDPW
QIDVALTKDLLQEYNLRAHASLGLSAATDVTSTDPAIVAKGDELLRKATD
VLYALGGSELCGVIYCALGKYPGPASRENRANSVAAMQRLADYAADKGIN
IDLEVVNRYETNIMNTGLEGLAFLDEVNRPNAFLHLDTYHMNIEENGMAK
SVLAAGDRLGYVHIGESHRGYLGTGNVDFASFFAALKQIDYRGPITFESF
SSEIVDPKLSNTLCVWRNLWHDSDDLAGKALEFIKQRL
Ligand information
Ligand IDFUD
InChIInChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1
InChIKeyBJHIKXHVCXFQLS-UYFOZJQFSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO
ACDLabs 10.04O=C(C(O)C(O)C(O)CO)CO
OpenEye OEToolkits 1.5.0C(C(C(C(C(=O)CO)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@H]([C@H]([C@@H](C(=O)CO)O)O)O)O
CACTVS 3.341OC[CH](O)[CH](O)[CH](O)C(=O)CO
FormulaC6 H12 O6
NameD-fructose
ChEMBLCHEMBL1232863
DrugBank
ZINCZINC000001532049
PDB chain7cj9 Chain C Residue 305 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7cj9 Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Resolution1.58 Å
Binding residue
(original residue number in PDB)		S69 E152 E158 H188 H211 R217 E246 L261
Binding residue
(residue number reindexed from 1)		S71 E154 E160 H190 H213 R219 E248 L263
Annotation score5
Enzymatic activity
Enzyme Commision number 5.1.3.31: D-tagatose 3-epimerase.
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7cj9, PDBe:7cj9, PDBj:7cj9
PDBsum7cj9
PubMed33838083
UniProtA0A172U6X0|LR3E_METSD L-ribulose 3-epimerase (Gene Name=AYM39_05640)

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