Structure of PDB 7abo Chain C Binding Site BS02

Receptor Information
>7abo Chain C (length=499) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FQSMNRSALDFRHFVDHLRRQGDLVDVHTEVDANLEIGAITRRVYERRAP
APLFHNIRDSLPGARVLGAPAGLRADRARAHSRLALHFGLPEHSGPRDIV
AMLRAAMRAEPIAPRRLERGPVQENVWLGEQVDLTRFPVPLLHEQDGGRY
FGTYGFHVVQTPDGSWDSWSVGRLMLVDRNTLAGPTIPTQHIGIIREQWR
RLGKPTPWAMALGAPPAALAAAGMPLPEGVSEAGYVGALVGEPVEVVRTQ
TNGLWVPANTEIVLEGEISLDETALEGPMGEYHGYSFPIGKPQPLFHVHA
LSFRDQPILPICVAGTPPEEHHTIWGTMISAQLLDVAQNAGLPVDMVWCS
YEAATCWAVLSIDVQRLAALGTDAAAFAARVAETVFGSHAGHLVPKLILV
GNDIDVTEIDQVVWALATRAHPLHDHFAFPQIRDFPMVPYLDAEDKARGS
GGRLVINCLYPEQFAGQMRAATASFRHAYPTALRRRVEERWSDYGFGDA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7abo Chain C Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7abo Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		H188 E229
Binding residue
(residue number reindexed from 1)		H191 E232
Annotation score1
Enzymatic activity
Enzyme Commision number 4.1.1.93: pyrrole-2-carboxylate decarboxylase.
Gene Ontology
Molecular Function
GO:0008694 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GO:0016831 carboxy-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006744 ubiquinone biosynthetic process
GO:0009056 catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7abo, PDBe:7abo, PDBj:7abo
PDBsum7abo
PubMed33763291
UniProtQ9I6N5|P2CDC_PSEAE Pyrrole-2-carboxylic acid decarboxylase (Gene Name=hudA)

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