Structure of PDB 6ycs Chain C Binding Site BS02

Receptor Information
>6ycs Chain C (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQ
WSQLKEQISDIDDAVRKL
Ligand information
Receptor-Ligand Complex Structure
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PDB6ycs Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins.
Resolution3.05 Å
Binding residue
(original residue number in PDB)		F77 L82 R86 W89 P98 G99 R100 K101
Binding residue
(residue number reindexed from 1)		F18 L23 R27 W30 P39 G40 R41 K42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0060261 positive regulation of transcription initiation by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:6ycs, PDBe:6ycs, PDBj:6ycs
PDBsum6ycs
PubMed32202774
UniProtP53999|TCP4_HUMAN Activated RNA polymerase II transcriptional coactivator p15 (Gene Name=SUB1)

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