Structure of PDB 6xwg Chain C Binding Site BS02

Receptor Information
>6xwg Chain C (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDK
RQRNRCQYCRYQKCLAMGMKREAVQEERQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6xwg Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E153 G154 R161 R184 N185 R191
Binding residue
(residue number reindexed from 1)		E22 G23 R30 R53 N54 R60
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6xwg, PDBe:6xwg, PDBj:6xwg
PDBsum6xwg
PubMed32974652
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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