Structure of PDB 6xnx Chain C Binding Site BS02

Receptor Information
>6xnx Chain C (length=548) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKV
LLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRY
DSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKH
GSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSVLCCKPLCLML
ADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDE
KLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEV
WRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQ
LEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMMMNGNFARKLMT
QETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQY
SFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASE
GNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Receptor-Ligand Complex Structure
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PDB6xnx Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y485 K489 H501 K608 H609 G610 A720 G722 S723 R773 M847 M848 Q978
Binding residue
(residue number reindexed from 1)		Y26 K30 H42 K149 H150 G151 A261 G263 S264 R314 M388 M389 Q519
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6xnx, PDBe:6xnx, PDBj:6xnx
PDBsum6xnx
PubMed32945578
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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