Structure of PDB 6x3j Chain C Binding Site BS02

Receptor Information
>6x3j Chain C (length=209) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGPDPENILPIKGNRNLQFIKPTITNENILVGEYSYYDSKRGESFEDQVL
YHYEVIGDKLIIGRFCSIGPGTTFIMNGANHRMDGSTYPFHLFRMGWEKY
MPSLKDLPLKGDIEIGNDVWIGRDVTIMPGVKIGDGAIIAAEAVVTKNVA
PYSIVGGNPLKFIRKRFSDGVIEEWLALQWWNLDMKIINENLPFIINGDI
EMLKRKRKL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6x3j Chain C Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6x3j Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		N164 P165
Binding residue
(residue number reindexed from 1)		N158 P159
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.1.-
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6x3j, PDBe:6x3j, PDBj:6x3j
PDBsum6x3j
PubMed32968273
UniProtP26839|VATA_STAAU Virginiamycin A acetyltransferase (Gene Name=vat)

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