Structure of PDB 6wmp Chain C Binding Site BS02

Receptor Information
>6wmp Chain C (length=1196) Species: 376619 (Francisella tularensis subsp. holarctica LVS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHS
GLEIVLKQSFPVESKNGQYELHYVDYQIGEPTFDETECQVRGATYDAPLN
VKLRLVVYNKDALPNEKIVEDIREEYVYMGDIPLMTTNGTFIINGTERVV
VSQLHRSPGAFFSKDDSEEGAFSARIIPYRGSWLDFEFDSKGIIWARIDR
KRKFCATVILKALGYTQEQILENRGRYISDTLKYDLTRNTDEALVEIYKV
LRPGDPPAAASVKALFEGLFFIESRYSLSDIGRMKLNARLGSDKVSKDIY
TLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGL
YRVEKGIRESMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQD
NPLSEVTHKRRISALGPGGLSRDRAGFEVRDVHATHYGRLCPIETPEGPN
IGLINSLASYARVNDYGFLEAPYRKVVDGKVTDEIEYLSAIDEDNYVIAQ
ASTKLDENNHFVEDIIQCRSGGEAIFTESSRVQYMDVSAKQMVSAAAALI
PFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCIIA
RNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRP
IVNVGDKVEAGDILADGFATDFGELSLGHNLMVAFMPWNGYNFEDSILLS
ERIVKDDKYTSIHIEEFTCVARDTKLGPEEITADIPNVSESSLAKLDESG
IVHIGANVEAGDILVAKITPKAEQQLTPEERLLRAIFNEKASNVVDSSLR
MPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARKDFDEEFAVIES
VVKSSIEQEVVGEKVQNAREYYEEAKIAIDAKFEAKKKSITQSNELSPGV
LKTVKVFVAIKKRIQPGDKMAGRHGNKGVVSRVLPVEDMPYMEDGTPVDV
CLNPLGIPSRMNIGQILEAHLGLASYGLGKKIEKTLEKTRKAAELRKTLE
EVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFDGAKEEDIKSL
LKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARST
GSYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLREMLTVKSDDI
AGRSKMYKNIVDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wmp Structural Basis for Virulence Activation of Francisella tularensis.
Resolution2.98 Å
Binding residue
(original residue number in PDB)		R543 K1087 H1249
Binding residue
(residue number reindexed from 1)		R422 K927 H1089
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wmp, PDBe:6wmp, PDBj:6wmp
PDBsum6wmp
PubMed33217319
UniProtQ2A1M7|RPOB_FRATH DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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