Structure of PDB 6uzi Chain C Binding Site BS02

Receptor Information
>6uzi Chain C (length=470) Species: 1338011 (Elizabethkingia anophelis NUHP1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHMNQFDVAVIGSGPGGYVAAIRCAQLGFKTVIIEKYSTLGGTCLNVGC
IPSKALLDSSEHFENAKHTFATHGILIDEPKVDIAQMISRKNDVVDQTTK
GINFLMDKNKITVLQGVGSFESATQIKVTKADGSSEVIEAKNTIIATGSK
PSSLPFITLDKERVITSTEALNLKEVPKHLIVIGGGVIGLELGSVYLRLG
SDVTVVEYLDKIIPGMDGTLSKELQKTLKKQGMKFMLSTAVSGVERNGDT
VKVTAKDKKGEDVVVEGDYCLVSVGRRPYTDGLGLEKAGVELDERGRVKT
NDHLQTNVPNIYAIGDVVKGAMLAHKAEEEGVFVAETLAGEKPHVNYNLI
PGVVYTWPEVAGVGKTEEQLKEAGVAYKTGSFPMRALGRSRASMDTDGVI
KILADEKTDEILGVHMIGARAADMIAEAVVAMEFRASAEDIARISHAHPT
YTEAIKEAALDATGKRAIHM
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6uzi Chain C Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6uzi Crystal structure of Dihydrolipoyl dehydrogenase from Elizabethkingia anophelis NUHP1
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H445 E450
Binding residue
(residue number reindexed from 1)		H448 E453
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) C42 C47 S50 V184 E188 H445 E450
Catalytic site (residue number reindexed from 1) C45 C50 S53 V187 E191 H448 E453
Enzyme Commision number 1.8.1.4: dihydrolipoyl dehydrogenase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004148 dihydrolipoyl dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0046872 metal ion binding
GO:0050660 flavin adenine dinucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:6uzi, PDBe:6uzi, PDBj:6uzi
PDBsum6uzi
PubMed
UniProtA0A077ELH4

[Back to BioLiP]