Structure of PDB 6u6y Chain C Binding Site BS02
Receptor Information
>6u6y Chain C (length=431) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNR
FEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFS
HMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEED
ICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNNGIDVAKWDYFARDCHHL
GIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRA
YQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLT
DNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDY
ESLPKEVASAKPKVLLDVKLKAEDFIVDVINMVSFYCKTAPNRAIEQLIR
VYCKKVDRKSLYAARQYFVQWCADRNFTKPQ
Ligand information
>6u6y Chain F (length=4) [
Search RNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
cgcc
....
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6u6y
Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Resolution
2.47 Å
Binding residue
(original residue number in PDB)
Y155 V156 H376 V378 R451
Binding residue
(residue number reindexed from 1)
Y41 V42 H253 V255 R328
Enzymatic activity
Enzyme Commision number
3.1.5.-
External links
PDB
RCSB:6u6y
,
PDBe:6u6y
,
PDBj:6u6y
PDBsum
6u6y
PubMed
33531504
UniProt
Q9Y3Z3
|SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (Gene Name=SAMHD1)
[
Back to BioLiP
]
