Structure of PDB 6qcx Chain C Binding Site BS02

Receptor Information
>6qcx Chain C (length=733) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRM
KWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVT
WWNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLL
NPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTM
ITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPG
GNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSC
LAAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIG
NGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDL
IILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFD
QWGYEESPKASELHGINESMNASDYTLKGVVVTRNVTEKVSITKNLSLIK
RTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKN
LVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQ
EVMKTDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENFIEVRKGSP
LFSYNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPD
LGDFKTIEELEKLKPGEKANILLYQGKPVKVVK
Ligand information
>6qcx Chain R (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uauaccucugcuucugcuauu
.....................
Receptor-Ligand Complex Structure
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PDB6qcx Structural snapshots of actively transcribing influenza polymerase.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		R40 E42 K43 R48 W51 R218
Binding residue
(residue number reindexed from 1)		R41 E43 K44 R49 W52 R219
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qcx, PDBe:6qcx, PDBj:6qcx
PDBsum6qcx
PubMed31160782
UniProtQ5V8X3

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