Structure of PDB 6qcs Chain C Binding Site BS02

Receptor Information
>6qcs Chain C (length=742) Species: 11520 (Influenza B virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRM
KWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVT
WWNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLL
NPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTM
ITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPG
GNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSC
LAAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIG
NGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDL
IILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFD
QWGYEESPKASELHGINESMNASDYTLKGVVVTRNVIDDFSSTETEKVSI
TKNLSLIKRTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQN
TYQWVLKNLVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARA
VLKQMRDQEVMKTDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENF
IEVRKGSPLFSYNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFL
VSGKYDPDLGDFKTIEELEKLKPGEKANILLYQGKPVKVVKR
Ligand information
Receptor-Ligand Complex Structure
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PDB6qcs Structural snapshots of actively transcribing influenza polymerase.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R40 E42 R48 W51
Binding residue
(residue number reindexed from 1)		R41 E43 R49 W52
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qcs, PDBe:6qcs, PDBj:6qcs
PDBsum6qcs
PubMed31160782
UniProtQ5V8X3

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