Structure of PDB 6pzv Chain C Binding Site BS02

Receptor Information
>6pzv Chain C (length=226) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPKCTECLQYLDDPELRYEQHPPDAVEEIQILTNERLSIFSYEDLPQHKL
TCFSVYCKRGHLCPIDTGLIEKDVELLFSGSAKPIYEDDPSPEGGINGKN
FGPINEWWIAGFDGGEKALLGFSTSFAEYILMDPSPEYAPLFSVMQEKIY
ISKIVVEFLQSNPDSTYEDLINKIETTVPPCMLNLNRFTEDSLLRHAQFV
VEQVESYDRAGFLSPCMRDLIKLAGV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6pzv Chain C Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6pzv Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Resolution3.01 Å
Binding residue
(original residue number in PDB)		C351 H416
Binding residue
(residue number reindexed from 1)		C4 H61
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
External links
PDB RCSB:6pzv, PDBe:6pzv, PDBj:6pzv
PDBsum6pzv
PubMed32675241
UniProtQ24K09|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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