Structure of PDB 6pa7 Chain C Binding Site BS02

Receptor Information
>6pa7 Chain C (length=108) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPN
IQSVLLPK
Ligand information
>6pa7 Chain J (length=166) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcggccgccacaggatgtatatatctgacacgtgcctggagactaggga
gtaatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgttta
agcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggat
tctccagggcggccga
Receptor-Ligand Complex Structure
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PDB6pa7 Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
Resolution2.94 Å
Binding residue
(original residue number in PDB)		K15 T16 R17 G28 R29 R32 R42 R77
Binding residue
(residue number reindexed from 1)		K5 T6 R7 G18 R19 R22 R32 R67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6pa7, PDBe:6pa7, PDBj:6pa7
PDBsum6pa7
PubMed32968275
UniProtP06897|H2A1_XENLA Histone H2A type 1

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