Structure of PDB 6ovr Chain C Binding Site BS02

Receptor Information
>6ovr Chain C (length=1107) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRE
TFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGL
IKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGR
YIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETL
ARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYV
YGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTL
RYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRE
RMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHK
RRISALGPGGLTRFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARV
DELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAE
RVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMG
SNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRI
VVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPAS
ENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIE
ARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSF
KGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDP
GVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHL
PDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKE
PEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEE
QLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTG
PYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIE
GRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDI
FEGLASK
Ligand information
Receptor-Ligand Complex Structure
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PDB6ovr Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Resolution2.843 Å
Binding residue
(original residue number in PDB)		Q390 Q393 F394 L413 T419 R420 I452 K838 K846 H999
Binding residue
(residue number reindexed from 1)		Q383 Q386 F387 L406 T412 R413 I441 K827 K835 H988
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ovr, PDBe:6ovr, PDBj:6ovr
PDBsum6ovr
PubMed31965171
UniProtQ8RQE9|RPOB_THET8 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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