Structure of PDB 6nw5 Chain C Binding Site BS02

Receptor Information
>6nw5 Chain C (length=331) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIRKLTEAFGPSGREEEVRSIILEELEGHIDGHRIDGLGNLIVWKGS
GEKKVILDAHIDEIGVVVTNVDDKGFLTIEPVGGVSPYMLLGKRIRFENG
TIGVVGMEGETTEERQENVRKLSFDKLFIDIGANSREEAQKMCPIGSFGV
YDSGFVEVSGKYVSKAMDDRIGCAVIVEVFKRIKPAVTLYGVFSVQEEVG
LVGASVAGYGVPADEAIAIDVTDSADTPKAIKRHAMRLSGGPALKVKDRA
SISSKRILENLIEIAEKFDIKYQMEVLTFGGTNAMGYQRTREGIPSATVS
IPTRYVHSPSEMIAPDDVEATVDLLIRYLGA
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain6nw5 Chain C Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6nw5 How metal cofactors drive dimer-dodecamer transition of the M42 aminopeptidase TmPep1050 ofThermotoga maritima.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D168 E198 H307
Binding residue
(residue number reindexed from 1)		D168 E198 H307
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6nw5, PDBe:6nw5, PDBj:6nw5
PDBsum6nw5
PubMed31611236
UniProtQ9X0E0

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