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Receptor Information

>6myq Chain C (length=139) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ATTAKEEMARFWEKNTKSSRPLSPHISIYKWSLPMAMSITHRGTGVALSL
GVSLFSLAALLLPEQFPHYVAVVKSLSLSPALIYSAKFALVFPLSYHTWN
GIRHLVWDMGKGFKLSQVEQSGVVVLILTLLSSAAIAAM

Ligand ID

9AU

InChI

InChI=1S/C24H30O3/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-21-23(25)20-13-5-6-14-22(20)27-24(21)26/h5-6,9,11,13-15,25H,7-8,10,12,16H2,1-4H3/b18-11+,19-15+

InChIKey

NJJDBBUWWOAOLD-CFBAGHHKSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 2.0.6	CC(=CCCC(=CCCC(=CCC1=C(c2ccccc2OC1=O)O)C)C)C
CACTVS 3.385	CC(C)=CCCC(C)=CCCC(C)=CCC1=C(O)c2ccccc2OC1=O
CACTVS 3.385	CC(C)=CCCC(/C)=C/CCC(/C)=C/CC1=C(O)c2ccccc2OC1=O
OpenEye OEToolkits 2.0.6	CC(=CCC/C(=C/CC/C(=C/CC1=C(c2ccccc2OC1=O)O)/C)/C)C

Formula

C24 H30 O3

Name

4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one

PDB chain

6myq Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6myq Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Resolution	1.97 Å
Binding residue (original residue number in PDB)	M36 I40
Binding residue (residue number reindexed from 1)	M35 I39
Annotation score	1

Enzyme Commision number

1.3.5.1: succinate dehydrogenase.

	Molecular Function
GO:0009055	electron transfer activity
GO:0046872	metal ion binding

	Biological Process
GO:0006099	tricarboxylic acid cycle

	Cellular Component
GO:0005739	mitochondrion
GO:0016020	membrane

PDB	RCSB:6myq, PDBe:6myq, PDBj:6myq
PDBsum	6myq
PubMed	34089891
UniProt	D0VWW3

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Structure of PDB 6myq Chain C Binding Site BS02