Structure of PDB 6k1m Chain C Binding Site BS02

Receptor Information
>6k1m Chain C (length=382) Species: 391008 (Stenotrophomonas maltophilia R551-3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RALALATLAIHGGQSPDPSTGAVMPPIYATSTYAQSSPGEHQGFEYSRTH
NPTRFAYERCVASLEGGTRGFAFASGMAASSTVIELLDAGSHVVAMDDIY
GGSFRLFERVRRRTAGLDFSFVDLTDLAAFEASITPKTKMVWIETPTNPM
LKIVDIAAVAAIAKRHGLIVVVDNTFASPMLQRPLELGADLVLHSATKYL
NGHSDMVGGMVVVGENAELAEQMAFLQNSVGGVQGPFDSFLALRGLKTLP
LRMKAHCANALALAQWLDKHPAVEKVIYPGLPSHPQHELAGRQMAGYGGI
VSIVLKGGFEAAKRFCEKTELFTLAESLGGVESLVNHPAVMTHASIPVAR
REQLGISDALVRLSVGVEDLGDLQVDLGEALK
Ligand information
Ligand IDPYR
InChIInChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChIKeyLCTONWCANYUPML-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385CC(=O)C(O)=O
OpenEye OEToolkits 1.7.6CC(=O)C(=O)O
ACDLabs 12.01O=C(C(=O)O)C
FormulaC3 H4 O3
NamePYRUVIC ACID
ChEMBLCHEMBL1162144
DrugBankDB00119
ZINCZINC000001532517
PDB chain6k1m Chain C Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6k1m Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Resolution2.32 Å
Binding residue
(original residue number in PDB)		Y108 K206 S335 T350 R370
Binding residue
(residue number reindexed from 1)		Y100 K198 S327 T342 R362
Annotation score5
Enzymatic activity
Enzyme Commision number 4.4.1.1: cystathionine gamma-lyase.
Gene Ontology
Molecular Function
GO:0003962 cystathionine gamma-synthase activity
GO:0004123 cystathionine gamma-lyase activity
GO:0016829 lyase activity
GO:0016846 carbon-sulfur lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0044540 L-cystine L-cysteine-lyase (deaminating)
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0019346 transsulfuration
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:6k1m, PDBe:6k1m, PDBj:6k1m
PDBsum6k1m
PubMed33497694
UniProtB4SII9

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