Structure of PDB 6h21 Chain C Binding Site BS02

Receptor Information

>6h21 Chain C (length=316) Species: 158879 (Staphylococcus aureus subsp. aureus N315) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MKKVSVIMPTFNNGEKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETL
NVIKKYKGLVRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHER
ALEDLYNYGKENNSDLIIGKYGVEGKGRSVPKAIFEKGNVAKADIIDNSI
FYALSVLKMFKKSVIDKNKIKFKTFSKTAEDQLFTIEFLMNSKNYSIKTD
YEYYIVVNDSTGNQYFATINEIYKAIYKSPIYKNQEKRHQLAGKYTTRLL
RHGQKKNFANSKMKYEDKIEWLNNFSKTINKVPRDSDKYVTQIFNLKLEA
IRQNDLLAVMIADKLL

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

6h21 Chain C Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6h21 Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Resolution	1.8 Å
Binding residue (original residue number in PDB)	D94 D95
Binding residue (residue number reindexed from 1)	D94 D95
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.4.1.-

Gene Ontology

	Molecular Function
GO:0016757	glycosyltransferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0019350	teichoic acid biosynthetic process
GO:0071555	cell wall organization

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Molecular Function

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Biological Process

External links

PDB	RCSB:6h21, PDBe:6h21, PDBj:6h21
PDBsum	6h21
PubMed	30464342
UniProt	A0A0H3JNB0\|TARP_STAAN Poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase TarP (Gene Name=tarP)

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