Structure of PDB 6h0f Chain C Binding Site BS02

Receptor Information
>6h0f Chain C (length=32) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGRGERPFQCNQCGASFTQKGNLLRHIKLHSG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6h0f Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6h0f Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.
Resolution3.25 Å
Binding residue
(original residue number in PDB)		C147 C150 H163 H167
Binding residue
(residue number reindexed from 1)		C10 C13 H26 H30
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6h0f, PDBe:6h0f, PDBj:6h0f
PDBsum6h0f
PubMed30385546
UniProtQ13422|IKZF1_HUMAN DNA-binding protein Ikaros (Gene Name=IKZF1)

[Back to BioLiP]