Structure of PDB 6gys Chain C Binding Site BS02

Receptor Information
>6gys Chain C (length=573) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTITASSSKEY
LPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQ
KDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNHSVDGK
YWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWEDGMQLV
MCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLANSLL
TQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPR
KPIALHTEVSSLLQHAAYLQDNSTEVLYWKIISLDRDLDQYLNKSSKPPL
KTLDAIRRELDIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWKLFKM
YLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRHPMVMQTITRVV
SFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTERLSKL
KLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLVP
LNSDFRTIVEEFQSEYNISDILS
Ligand information
>6gys Chain G (length=52) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttcttactatttcttttttaactttcggaaatcaaatacactaatatttt
aa
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gys Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		K35 R36 L275 L276 Y325 P366 K368 T369 A372
Binding residue
(residue number reindexed from 1)		K30 R31 L268 L269 Y318 P349 K351 T352 A355
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008301 DNA binding, bending
GO:0019237 centromeric DNA binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000921 septin ring assembly
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0051382 kinetochore assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031518 CBF3 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gys, PDBe:6gys, PDBj:6gys
PDBsum6gys
PubMed30478265
UniProtP40969|CBF3B_YEAST Centromere DNA-binding protein complex CBF3 subunit B (Gene Name=CEP3)

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