Structure of PDB 6fuw Chain C Binding Site BS02

Receptor Information
>6fuw Chain C (length=114) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMKSGAAVCEFFLKAACGK
GGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSK
FGECSNKECPFLHI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6fuw Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6fuw Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		C41 C55 H59
Binding residue
(residue number reindexed from 1)		C40 C54 H58
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6fuw, PDBe:6fuw, PDBj:6fuw
PDBsum6fuw
PubMed29358758
UniProtO95639|CPSF4_HUMAN Cleavage and polyadenylation specificity factor subunit 4 (Gene Name=CPSF4)

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