Structure of PDB 6czy Chain C Binding Site BS02

Receptor Information
>6czy Chain C (length=361) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSII
QKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTG
SWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICAN
ETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGP
SGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLV
FEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVP
FTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLV
AFMKDFQAKHA
Ligand information
Ligand IDPMP
InChIInChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChIKeyZMJGSOSNSPKHNH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1CN)C
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
FormulaC8 H13 N2 O5 P
Name4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE;
PYRIDOXAMINE-5'-PHOSPHATE
ChEMBLCHEMBL1235353
DrugBankDB02142
ZINCZINC000001532708
PDB chain6czy Chain D Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6czy Structural Analysis of Phosphoserine Aminotransferase (Isoform 1) FromArabidopsis thaliana- the Enzyme Involved in the Phosphorylated Pathway of Serine Biosynthesis.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		N306 T307
Binding residue
(residue number reindexed from 1)		N237 T238
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
Biological Process
GO:0006564 L-serine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6czy, PDBe:6czy, PDBj:6czy
PDBsum6czy
PubMed30034403
UniProtQ96255|SERB1_ARATH Phosphoserine aminotransferase 1, chloroplastic (Gene Name=PSAT1)

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